diff --git a/tensorrt_llm/_torch/modules/fused_moe/fused_moe_trtllm_gen.py b/tensorrt_llm/_torch/modules/fused_moe/fused_moe_trtllm_gen.py
index 94e082a6670..2a8e1c30ea8 100644
--- a/tensorrt_llm/_torch/modules/fused_moe/fused_moe_trtllm_gen.py
+++ b/tensorrt_llm/_torch/modules/fused_moe/fused_moe_trtllm_gen.py
@@ -2,6 +2,8 @@
 
 import torch
 
+from tensorrt_llm._utils import get_sm_version
+
 from ...distributed.ops import reducescatter
 from ...model_config import ModelConfig
 from ...utils import Fp4QuantizedTensor
@@ -68,6 +70,11 @@ def __init__(
             weight_loading_mode=weight_loading_mode,
         )
 
+        sm_version = get_sm_version()
+        if sm_version >= 120:
+            raise NotImplementedError(
+                "TRTLLMGenFusedMoE does not support SM120 and above.")
+
         assert not self.smart_router, "Smart router is not supported in TRTLLMGenFusedMoE."
 
         self.num_slots = self.num_experts
diff --git a/tests/integration/defs/accuracy/test_llm_api_pytorch.py b/tests/integration/defs/accuracy/test_llm_api_pytorch.py
index 5112907c209..42e6fe0f7db 100644
--- a/tests/integration/defs/accuracy/test_llm_api_pytorch.py
+++ b/tests/integration/defs/accuracy/test_llm_api_pytorch.py
@@ -1334,6 +1334,11 @@ def test_nvfp4_4gpus_online_eplb(self, fp8kv):
     @parametrize_with_ids("moe_backend", ["CUTLASS", "TRTLLM"])
     def test_nvfp4(self, fp8kv, attention_dp, cuda_graph, overlap_scheduler,
                    torch_compile, mtp_nextn, moe_backend):
+        if moe_backend == "TRTLLM" and (get_sm_version() == 120
+                                        or get_sm_version() == 121):
+            pytest.skip(
+                "MOE TRTLLM backend does not support SM version 120 or 121")
+
         kv_cache_config = KvCacheConfig(free_gpu_memory_fraction=0.75)
         torch_compile_config = TorchCompileConfig(
             enable_fullgraph=True,
@@ -1381,8 +1386,10 @@ def test_nvfp4_4gpus(self, fp8kv, attention_dp, cuda_graph,
                          torch_compile, mtp_nextn, moe_backend):
         if torch_compile and pp_size > 1:
             pytest.skip("PP with torch.compile is not supported yet.")
-        if moe_backend == "TRTLLM" and get_sm_version() == 120:
-            pytest.skip("MOE TRTLLM backend does not support SM version 120")
+        if moe_backend == "TRTLLM" and (get_sm_version() == 120
+                                        or get_sm_version() == 121):
+            pytest.skip(
+                "MOE TRTLLM backend does not support SM version 120 or 121")
         kv_cache_config = KvCacheConfig(free_gpu_memory_fraction=0.75)
         # Picewise Cuda Graph cannot be enabled for nvfp4 attention dp.
         torch_compile_config = TorchCompileConfig(
@@ -1597,6 +1604,11 @@ class TestDeepSeekR1(LlmapiAccuracyTestHarness):
     def test_nvfp4_multi_gpus(self, tp_size, pp_size, ep_size, mtp_nextn, fp8kv,
                               attention_dp, cuda_graph, overlap_scheduler,
                               max_batch_size, moe_backend):
+        if moe_backend == "TRTLLM" and (get_sm_version() == 120
+                                        or get_sm_version() == 121):
+            pytest.skip(
+                "MOE TRTLLM backend does not support SM version 120 or 121")
+
         kv_cache_config = KvCacheConfig(free_gpu_memory_fraction=0.70)
         pytorch_config = dict(
             disable_overlap_scheduler=not overlap_scheduler,
@@ -2153,6 +2165,11 @@ def test_nvfp4(
         torch_compile,
     ):
 
+        if moe_backend == "TRTLLM" and (get_sm_version() == 120
+                                        or get_sm_version() == 121):
+            pytest.skip(
+                "MOE TRTLLM backend does not support SM version 120 or 121")
+
         torch_compile_config = TorchCompileConfig(
             enable_fullgraph=True,
             enable_piecewise_cuda_graph=cuda_graph and not attention_dp,
@@ -2273,6 +2290,11 @@ def test_fp8(self, tp_size, pp_size, ep_size, attention_dp, cuda_graph,
     def test_nvfp4(self, tp_size, pp_size, ep_size, attention_dp, cuda_graph,
                    overlap_scheduler, moe_backend, eagle3):
 
+        if moe_backend == "TRTLLM" and (get_sm_version() == 120
+                                        or get_sm_version() == 121):
+            pytest.skip(
+                "MOE TRTLLM backend does not support SM version 120 or 121")
+
         pytorch_config = dict(
             disable_overlap_scheduler=not overlap_scheduler,
             cuda_graph_config=CudaGraphConfig() if cuda_graph else None,
diff --git a/tests/integration/test_lists/qa/llm_function_rtx6kd.txt b/tests/integration/test_lists/qa/llm_function_rtx6kd.txt
index fbabac6b84f..d30cd857dea 100644
--- a/tests/integration/test_lists/qa/llm_function_rtx6kd.txt
+++ b/tests/integration/test_lists/qa/llm_function_rtx6kd.txt
@@ -24,8 +24,6 @@ accuracy/test_llm_api_pytorch.py::TestDeepSeekV3Lite::test_nvfp4[moe_backend=CUT
 accuracy/test_llm_api_pytorch.py::TestLlama3_1_8B::test_nvfp4
 accuracy/test_llm_api_pytorch.py::TestQwen3_30B_A3B::test_nvfp4[latency_moe_cutlass-torch_compile=False]
 accuracy/test_llm_api_pytorch.py::TestQwen3_30B_A3B::test_nvfp4[latency_moe_cutlass-torch_compile=True]
-accuracy/test_llm_api_pytorch.py::TestQwen3_30B_A3B::test_nvfp4[latency_moe_trtllm-torch_compile=False]
-accuracy/test_llm_api_pytorch.py::TestQwen3_30B_A3B::test_nvfp4[latency_moe_trtllm-torch_compile=True]
 test_e2e.py::test_ptp_quickstart_advanced_mixed_precision
 test_e2e.py::test_ptp_quickstart_advanced[Llama3.1-8B-BF16-llama-3.1-model/Meta-Llama-3.1-8B]
 test_e2e.py::test_ptp_quickstart_advanced[Llama3.1-8B-FP8-llama-3.1-model/Llama-3.1-8B-Instruct-FP8]