diff --git a/src/libraries/System.Private.CoreLib/src/System/Runtime/CompilerServices/ConfiguredCancelableAsyncEnumerable.cs b/src/libraries/System.Private.CoreLib/src/System/Runtime/CompilerServices/ConfiguredCancelableAsyncEnumerable.cs
index c874d3fc1f485f..fdf8ae7965feae 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Runtime/CompilerServices/ConfiguredCancelableAsyncEnumerable.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Runtime/CompilerServices/ConfiguredCancelableAsyncEnumerable.cs
@@ -10,6 +10,9 @@ namespace System.Runtime.CompilerServices
     /// <summary>Provides an awaitable async enumerable that enables cancelable iteration and configured awaits.</summary>
     [StructLayout(LayoutKind.Auto)]
     public readonly struct ConfiguredCancelableAsyncEnumerable<T>
+#if NET10_0_OR_GREATER
+        where T : allows ref struct
+#endif
     {
         private readonly IAsyncEnumerable<T> _enumerable;
         private readonly CancellationToken _cancellationToken;
diff --git a/src/libraries/System.Private.CoreLib/src/System/Threading/Tasks/TaskAsyncEnumerableExtensions.cs b/src/libraries/System.Private.CoreLib/src/System/Threading/Tasks/TaskAsyncEnumerableExtensions.cs
index 796080a24e7472..2841a334b23f12 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Threading/Tasks/TaskAsyncEnumerableExtensions.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Threading/Tasks/TaskAsyncEnumerableExtensions.cs
@@ -22,8 +22,11 @@ public static ConfiguredAsyncDisposable ConfigureAwait(this IAsyncDisposable sou
         /// <param name="continueOnCapturedContext"><see langword="true" /> to capture and marshal back to the current context; otherwise, <see langword="false" />.</param>
         /// <returns>The configured enumerable.</returns>
         public static ConfiguredCancelableAsyncEnumerable<T> ConfigureAwait<T>(
-            this IAsyncEnumerable<T> source, bool continueOnCapturedContext) =>
-            new ConfiguredCancelableAsyncEnumerable<T>(source, continueOnCapturedContext, cancellationToken: default);
+            this IAsyncEnumerable<T> source, bool continueOnCapturedContext)
+#if NET10_0_OR_GREATER
+            where T : allows ref struct
+#endif
+            => new ConfiguredCancelableAsyncEnumerable<T>(source, continueOnCapturedContext, cancellationToken: default);
 
         /// <summary>Sets the <see cref="CancellationToken"/> to be passed to <see cref="IAsyncEnumerable{T}.GetAsyncEnumerator(CancellationToken)"/> when iterating.</summary>
         /// <typeparam name="T">The type of the objects being iterated.</typeparam>
@@ -31,7 +34,10 @@ public static ConfiguredCancelableAsyncEnumerable<T> ConfigureAwait<T>(
         /// <param name="cancellationToken">The <see cref="CancellationToken"/> to use.</param>
         /// <returns>The configured enumerable.</returns>
         public static ConfiguredCancelableAsyncEnumerable<T> WithCancellation<T>(
-            this IAsyncEnumerable<T> source, CancellationToken cancellationToken) =>
-            new ConfiguredCancelableAsyncEnumerable<T>(source, continueOnCapturedContext: true, cancellationToken);
+            this IAsyncEnumerable<T> source, CancellationToken cancellationToken)
+#if NET10_0_OR_GREATER
+            where T : allows ref struct
+#endif
+            => new ConfiguredCancelableAsyncEnumerable<T>(source, continueOnCapturedContext: true, cancellationToken);
     }
 }
diff --git a/src/libraries/System.Runtime/ref/System.Runtime.cs b/src/libraries/System.Runtime/ref/System.Runtime.cs
index 5f8847cf2f4518..0fcc4bd3639540 100644
--- a/src/libraries/System.Runtime/ref/System.Runtime.cs
+++ b/src/libraries/System.Runtime/ref/System.Runtime.cs
@@ -13298,6 +13298,7 @@ public readonly partial struct ConfiguredAsyncDisposable
         public System.Runtime.CompilerServices.ConfiguredValueTaskAwaitable DisposeAsync() { throw null; }
     }
     public readonly partial struct ConfiguredCancelableAsyncEnumerable<T>
+        where T : allows ref struct
     {
         private readonly object _dummy;
         private readonly int _dummyPrimitive;
@@ -15983,10 +15984,10 @@ public static void WaitAll(System.Threading.Tasks.Task[] tasks, System.Threading
     public static partial class TaskAsyncEnumerableExtensions
     {
         public static System.Runtime.CompilerServices.ConfiguredAsyncDisposable ConfigureAwait(this System.IAsyncDisposable source, bool continueOnCapturedContext) { throw null; }
-        public static System.Runtime.CompilerServices.ConfiguredCancelableAsyncEnumerable<T> ConfigureAwait<T>(this System.Collections.Generic.IAsyncEnumerable<T> source, bool continueOnCapturedContext) { throw null; }
+        public static System.Runtime.CompilerServices.ConfiguredCancelableAsyncEnumerable<T> ConfigureAwait<T>(this System.Collections.Generic.IAsyncEnumerable<T> source, bool continueOnCapturedContext) where T : allows ref struct { throw null; }
         [System.Runtime.Versioning.UnsupportedOSPlatformAttribute("browser")]
         public static System.Collections.Generic.IEnumerable<T> ToBlockingEnumerable<T>(this System.Collections.Generic.IAsyncEnumerable<T> source, System.Threading.CancellationToken cancellationToken = default(System.Threading.CancellationToken)) { throw null; }
-        public static System.Runtime.CompilerServices.ConfiguredCancelableAsyncEnumerable<T> WithCancellation<T>(this System.Collections.Generic.IAsyncEnumerable<T> source, System.Threading.CancellationToken cancellationToken) { throw null; }
+        public static System.Runtime.CompilerServices.ConfiguredCancelableAsyncEnumerable<T> WithCancellation<T>(this System.Collections.Generic.IAsyncEnumerable<T> source, System.Threading.CancellationToken cancellationToken) where T : allows ref struct { throw null; }
     }
     public partial class TaskCanceledException : System.OperationCanceledException
     {