diff --git a/eng/pipelines/extra-platforms/runtime-extra-platforms-maccatalyst.yml b/eng/pipelines/extra-platforms/runtime-extra-platforms-maccatalyst.yml
index 4ffece996d9cdc..8b1b2dbc59962c 100644
--- a/eng/pipelines/extra-platforms/runtime-extra-platforms-maccatalyst.yml
+++ b/eng/pipelines/extra-platforms/runtime-extra-platforms-maccatalyst.yml
@@ -43,6 +43,55 @@ jobs:
             creator: dotnet-bot
             testRunNamePrefixSuffix: Mono_$(_BuildConfig)
 
+#
+# MacCatalyst interp - requires AOT Compilation and Interp flags
+# Build the whole product using Mono and run runtime tests
+#
+- template: /eng/pipelines/common/platform-matrix.yml
+  parameters:
+    jobTemplate: /eng/pipelines/common/global-build-job.yml
+    helixQueuesTemplate: /eng/pipelines/coreclr/templates/helix-queues-setup.yml
+    buildConfig: Release
+    runtimeFlavor: mono
+    isExtraPlatformsBuild: ${{ parameters.isExtraPlatformsBuild }}
+    isiOSLikeOnlyBuild: ${{ parameters.isiOSLikeOnlyBuild }}
+    platforms:
+      - maccatalyst_x64
+      - maccatalyst_arm64
+    variables:
+      # map dependencies variables to local variables
+      - name: librariesContainsChange
+        value: $[ stageDependencies.EvaluatePaths.evaluate_paths.outputs['SetPathVars_libraries.containsChange'] ]
+      - name: monoContainsChange
+        value: $[ stageDependencies.EvaluatePaths.evaluate_paths.outputs['SetPathVars_mono_excluding_wasm.containsChange'] ]
+      - ${{ if and(eq(variables['System.TeamProject'], 'public'), eq(variables['Build.Reason'], 'PullRequest')) }}:
+        - name: _HelixSource
+          value: pr/dotnet/runtime/$(Build.SourceBranch)
+      - ${{ if and(eq(variables['System.TeamProject'], 'public'), ne(variables['Build.Reason'], 'PullRequest')) }}:
+        - name: _HelixSource
+          value: ci/dotnet/runtime/$(Build.SourceBranch)
+      - name: timeoutPerTestInMinutes
+        value: 60
+      - name: timeoutPerTestCollectionInMinutes
+        value: 180
+    jobParameters:
+      testGroup: innerloop
+      nameSuffix: AllSubsets_Mono_RuntimeTests
+      buildArgs: -s mono+libs -c $(_BuildConfig)
+      timeoutInMinutes: 240
+      # extra steps, run tests
+      extraVariablesTemplates:
+        - template: /eng/pipelines/common/templates/runtimes/test-variables.yml
+          parameters:
+            testGroup: innerloop
+      postBuildSteps:
+        - template: /eng/pipelines/common/templates/runtimes/build-runtime-tests-and-send-to-helix.yml
+          parameters:
+            creator: dotnet-bot
+            testBuildArgs: /p:DevTeamProvisioning=adhoc /p:RunAOTCompilation=true /p:MonoForceInterpreter=true
+            compileOnHelix: true
+            testRunNamePrefixSuffix: Mono_$(_BuildConfig)
+
 #
 # MacCatalyst interp - requires AOT Compilation and Interp flags
 # Build the whole product using Mono and run libraries tests
diff --git a/src/mono/msbuild/apple/build/AppleBuild.targets b/src/mono/msbuild/apple/build/AppleBuild.targets
index f219652d697631..c686768b27621a 100644
--- a/src/mono/msbuild/apple/build/AppleBuild.targets
+++ b/src/mono/msbuild/apple/build/AppleBuild.targets
@@ -7,6 +7,7 @@
     <_ProcessRuntimeComponentsForLibraryMode Condition="'$(_IsLibraryMode)' == 'true' and '$(UseNativeAOTRuntime)' != 'true'">_ProcessRuntimeComponentsForLibraryMode</_ProcessRuntimeComponentsForLibraryMode>
     <EnableDefaultAssembliesToBundle Condition="'$(EnableDefaultAssembliesToBundle)' == ''">false</EnableDefaultAssembliesToBundle>
     <UseSystemZlib Condition="'$(TargetOS)' == 'ios' or '$(TargetOS)' == 'iossimulator' or '$(TargetOS)' == 'tvos' or '$(TargetOS)' == 'tvossimulator' or '$(TargetOS)' == 'maccatalyst' or '$(TargetOS)' == 'android' or '$(TargetArchitecture)' == 'armv6'">true</UseSystemZlib>
+    <UseMonoRuntime Condition="'$(RuntimeFlavor)' == 'mono'">true</UseMonoRuntime>
   </PropertyGroup>
 
   <UsingTask Condition="'$(AppleGenerateAppBundle)' == 'true'"
diff --git a/src/tests/Common/XHarnessRunnerLibrary/RunnerEntryPoint.cs b/src/tests/Common/XHarnessRunnerLibrary/RunnerEntryPoint.cs
index 03e8a6b35fcd6c..90a8cc25dc5946 100644
--- a/src/tests/Common/XHarnessRunnerLibrary/RunnerEntryPoint.cs
+++ b/src/tests/Common/XHarnessRunnerLibrary/RunnerEntryPoint.cs
@@ -79,7 +79,7 @@ public AppleEntryPoint(
         protected override bool IsXunit => true;
         protected override TestRunner GetTestRunner(LogWriter logWriter)
         {
-            var runner = new GeneratedTestRunner(logWriter, _runTestsCallback, _assemblyName, _testExclusionTable, writeBase64TestResults: true);
+            var runner = new GeneratedTestRunner(logWriter, _runTestsCallback, _assemblyName, _testExclusionTable, writeBase64TestResults: false);
             if (_methodNameToRun is not null)
             {
                 runner.SkipMethod(_methodNameToRun, isExcluded: false);
diff --git a/src/tests/Directory.Build.targets b/src/tests/Directory.Build.targets
index 7546b5a10d679b..3a69601660014f 100644
--- a/src/tests/Directory.Build.targets
+++ b/src/tests/Directory.Build.targets
@@ -20,8 +20,6 @@
 
     <!-- Merged test runner assemblies might not have any non-generated sources, and that's okay -->
     <NoWarn Condition="'$(IsMergedTestRunnerAssembly)' == 'true'">$(NoWarn);CS2008</NoWarn>
-
-    <IncludesTestRunner Condition="'$(TargetsAppleMobile)' == 'true'">false</IncludesTestRunner>
   </PropertyGroup>
 
   <!-- All CLRTests need to be of a certain "kind". These kinds are enumerated below.
diff --git a/src/tests/JIT/Directed/coverage/compiler/FilterToHandler.il b/src/tests/JIT/Directed/coverage/compiler/FilterToHandler.il
index 0175d39a833c4d..b7727e7b11d377 100644
--- a/src/tests/JIT/Directed/coverage/compiler/FilterToHandler.il
+++ b/src/tests/JIT/Directed/coverage/compiler/FilterToHandler.il
@@ -9,6 +9,8 @@
   .ver 4:0:0:0
 }
 .assembly extern xunit.core {}
+.assembly extern Microsoft.DotNet.XUnitExtensions { .publickeytoken = (31 BF 38 56 AD 36 4E 35 ) }
+.assembly extern TestLibrary { .ver 0:0:0:0 }
 .assembly extern mscorlib {}
 .assembly extern common {}
 .assembly 'FilterToHandler' {}
@@ -57,9 +59,12 @@ done2:
 
 .class public auto ansi FilterToHandler {
 .method public static int32 Main() {
-.custom instance void [xunit.core]Xunit.FactAttribute::.ctor() = (
-    01 00 00 00
-)
+.custom instance void [xunit.core]Xunit.FactAttribute::.ctor() = {}
+.custom instance void [Microsoft.DotNet.XUnitExtensions]Xunit.ActiveIssueAttribute::.ctor(string, class [mscorlib]System.Type, string[]) = {
+    string('https://github.com/dotnet/runtime/issues/114902')
+    type([TestLibrary]TestLibrary.PlatformDetection)
+    string[1] ('IsAppleMobile')
+}
 .entrypoint
 .maxstack	20
   .try
diff --git a/src/tests/JIT/Regression/JitBlue/GitHub_21990/GitHub_21990.cs b/src/tests/JIT/Regression/JitBlue/GitHub_21990/GitHub_21990.cs
index 854d0f0e5882fd..6d107a54cebd25 100644
--- a/src/tests/JIT/Regression/JitBlue/GitHub_21990/GitHub_21990.cs
+++ b/src/tests/JIT/Regression/JitBlue/GitHub_21990/GitHub_21990.cs
@@ -5,6 +5,7 @@
 using System;
 using System.Runtime.CompilerServices;
 using Xunit;
+using TestLibrary;
 
 // Test to stress FP-relative addressing of generics context slot on ARM64. "str" instruction has a 32760 byte offset limit.
 // And normally, the frame pointer is at the bottom of the frame and the stored generics context at the top. If the locals
@@ -573,6 +574,7 @@ public static int TestGenericContext<T>(int x)
     }
 
     [Fact]
+    [ActiveIssue("https://github.com/dotnet/runtime/issues/46622", typeof(PlatformDetection), nameof(PlatformDetection.IsAppleMobile))]
     public static int TestEntryPoint()
     {
         const int Pass = 100;
diff --git a/src/tests/JIT/Regression/JitBlue/GitHub_21990/GitHub_21990.csproj b/src/tests/JIT/Regression/JitBlue/GitHub_21990/GitHub_21990.csproj
index 501217e4d86892..a4dc1b8fae4df9 100644
--- a/src/tests/JIT/Regression/JitBlue/GitHub_21990/GitHub_21990.csproj
+++ b/src/tests/JIT/Regression/JitBlue/GitHub_21990/GitHub_21990.csproj
@@ -6,4 +6,7 @@
   <ItemGroup>
     <Compile Include="$(MSBuildProjectName).cs" />
   </ItemGroup>
+  <ItemGroup>
+    <ProjectReference Include="$(TestSourceDir)Common/CoreCLRTestLibrary/CoreCLRTestLibrary.csproj" />
+  </ItemGroup>
 </Project>
diff --git a/src/tests/JIT/Regression/JitBlue/GitHub_23791/GitHub_23791.cs b/src/tests/JIT/Regression/JitBlue/GitHub_23791/GitHub_23791.cs
index 81a234637a5c41..d012cc00c46c41 100644
--- a/src/tests/JIT/Regression/JitBlue/GitHub_23791/GitHub_23791.cs
+++ b/src/tests/JIT/Regression/JitBlue/GitHub_23791/GitHub_23791.cs
@@ -5,6 +5,7 @@
 using System;
 using System.Runtime.CompilerServices;
 using Xunit;
+using TestLibrary;
 
 // The jit should null check 'this' in NextElement
 
@@ -16,6 +17,7 @@ public unsafe struct GitHub_23791
     byte NextElement(int i) => A[1+i];
 
     [Fact]
+    [ActiveIssue("https://github.com/dotnet/runtime/issues/114908", typeof(PlatformDetection), nameof(PlatformDetection.IsAppleMobile))]
     public static int TestEntryPoint() 
     {
         int result = -1;
diff --git a/src/tests/JIT/Regression/JitBlue/GitHub_23791/GitHub_23791.csproj b/src/tests/JIT/Regression/JitBlue/GitHub_23791/GitHub_23791.csproj
index f5f3ecae247d5f..ffbec1f22cc308 100644
--- a/src/tests/JIT/Regression/JitBlue/GitHub_23791/GitHub_23791.csproj
+++ b/src/tests/JIT/Regression/JitBlue/GitHub_23791/GitHub_23791.csproj
@@ -7,4 +7,7 @@
   <ItemGroup>
     <Compile Include="$(MSBuildProjectName).cs" />
   </ItemGroup>
+  <ItemGroup>
+    <ProjectReference Include="$(TestSourceDir)Common/CoreCLRTestLibrary/CoreCLRTestLibrary.csproj" />
+  </ItemGroup>
 </Project>
diff --git a/src/tests/JIT/Regression/JitBlue/GitHub_27678/GitHub_27678.il b/src/tests/JIT/Regression/JitBlue/GitHub_27678/GitHub_27678.il
index dd4ddac38e011b..b889a89b2f20e4 100644
--- a/src/tests/JIT/Regression/JitBlue/GitHub_27678/GitHub_27678.il
+++ b/src/tests/JIT/Regression/JitBlue/GitHub_27678/GitHub_27678.il
@@ -22,6 +22,8 @@
 .assembly extern System.Diagnostics.Debug {}
 .assembly GitHub_27678 {}
 .assembly extern xunit.core {}
+.assembly extern Microsoft.DotNet.XUnitExtensions { .publickeytoken = (31 BF 38 56 AD 36 4E 35 ) }
+.assembly extern TestLibrary { .ver 0:0:0:0 }
 
 .class private sequential ansi sealed beforefieldinit AStruct
        extends [System.Runtime]System.ValueType
@@ -167,9 +169,12 @@
 
   .method public hidebysig static int32  Main() cil managed
   {
-    .custom instance void [xunit.core]Xunit.FactAttribute::.ctor() = (
-        01 00 00 00
-    )
+    .custom instance void [xunit.core]Xunit.FactAttribute::.ctor() = {}
+    .custom instance void [Microsoft.DotNet.XUnitExtensions]Xunit.ActiveIssueAttribute::.ctor(string, class [mscorlib]System.Type, string[]) = {
+        string('https://github.com/dotnet/runtime/issues/114908')
+        type([TestLibrary]TestLibrary.PlatformDetection)
+        string[1] ('IsAppleMobile')
+    }
     .entrypoint
     // Code size       62 (0x3e)
     .maxstack  3
diff --git a/src/tests/JIT/Regression/JitBlue/GitHub_35384/GitHub_35384.il b/src/tests/JIT/Regression/JitBlue/GitHub_35384/GitHub_35384.il
index 9391210ea07a43..65c7948aea41d9 100644
--- a/src/tests/JIT/Regression/JitBlue/GitHub_35384/GitHub_35384.il
+++ b/src/tests/JIT/Regression/JitBlue/GitHub_35384/GitHub_35384.il
@@ -6,6 +6,8 @@
 .assembly extern System.Runtime { .publickeytoken = (B0 3F 5F 7F 11 D5 0A 3A ) }
 .assembly GitHub_35384 {}
 .assembly extern xunit.core {}
+.assembly extern Microsoft.DotNet.XUnitExtensions { .publickeytoken = (31 BF 38 56 AD 36 4E 35 ) }
+.assembly extern TestLibrary { .ver 0:0:0:0 }
 
 .class private sequential ansi sealed beforefieldinit Struct
        extends [System.Runtime]System.ValueType
@@ -40,9 +42,12 @@
   
   .method public hidebysig static int32 Main() cil managed
   {
-    .custom instance void [xunit.core]Xunit.FactAttribute::.ctor() = (
-        01 00 00 00
-    )
+    .custom instance void [xunit.core]Xunit.FactAttribute::.ctor() = {}
+    .custom instance void [Microsoft.DotNet.XUnitExtensions]Xunit.ActiveIssueAttribute::.ctor(string, class [mscorlib]System.Type, string[]) = {
+        string('https://github.com/dotnet/runtime/issues/114908')
+        type([TestLibrary]TestLibrary.PlatformDetection)
+        string[1] ('IsAppleMobile')
+    }
     .entrypoint
     .maxstack 1
     call       string Program::ValueTypeExplicitThisInstanceMethodCalli()
diff --git a/src/tests/JIT/Regression/JitBlue/GitHub_4044/GitHub_4044.cs b/src/tests/JIT/Regression/JitBlue/GitHub_4044/GitHub_4044.cs
index a23dcfa21865e4..34447a091c1161 100644
--- a/src/tests/JIT/Regression/JitBlue/GitHub_4044/GitHub_4044.cs
+++ b/src/tests/JIT/Regression/JitBlue/GitHub_4044/GitHub_4044.cs
@@ -4,10 +4,12 @@
 using System;
 using System.Runtime.CompilerServices;
 using Xunit;
+using TestLibrary;
 
 public class C
 {
     [Fact]
+    [ActiveIssue("https://github.com/dotnet/runtime/issues/114908", typeof(PlatformDetection), nameof(PlatformDetection.IsAppleMobile))]
     public static int TestEntryPoint()
     {
         int error = Test1();
diff --git a/src/tests/JIT/Regression/JitBlue/GitHub_4044/GitHub_4044.csproj b/src/tests/JIT/Regression/JitBlue/GitHub_4044/GitHub_4044.csproj
index de6d5e08882e86..d50b23efc171bb 100644
--- a/src/tests/JIT/Regression/JitBlue/GitHub_4044/GitHub_4044.csproj
+++ b/src/tests/JIT/Regression/JitBlue/GitHub_4044/GitHub_4044.csproj
@@ -5,4 +5,7 @@
   <ItemGroup>
     <Compile Include="$(MSBuildProjectName).cs" />
   </ItemGroup>
+  <ItemGroup>
+    <ProjectReference Include="$(TestSourceDir)Common/CoreCLRTestLibrary/CoreCLRTestLibrary.csproj" />
+  </ItemGroup>
 </Project>
diff --git a/src/tests/JIT/opt/Structs/MemsetMemcpyNullref.cs b/src/tests/JIT/opt/Structs/MemsetMemcpyNullref.cs
index 0d18e7bf535145..2faafae90705f2 100644
--- a/src/tests/JIT/opt/Structs/MemsetMemcpyNullref.cs
+++ b/src/tests/JIT/opt/Structs/MemsetMemcpyNullref.cs
@@ -4,10 +4,12 @@
 using System;
 using System.Runtime.CompilerServices;
 using Xunit;
+using TestLibrary;
 
 public unsafe class MemsetMemcpyNullref
 {
     [Fact]
+    [ActiveIssue("https://github.com/dotnet/runtime/issues/98628", typeof(PlatformDetection), nameof(PlatformDetection.IsAppleMobile))]
     public static void MemsetMemcpyThrowNullRefonNull()
     {
         Assert.Throws<NullReferenceException>(() => MemoryInit(null));
diff --git a/src/tests/JIT/opt/Structs/MemsetMemcpyNullref.csproj b/src/tests/JIT/opt/Structs/MemsetMemcpyNullref.csproj
index 23d7b90be5361c..8291bcb99a776b 100644
--- a/src/tests/JIT/opt/Structs/MemsetMemcpyNullref.csproj
+++ b/src/tests/JIT/opt/Structs/MemsetMemcpyNullref.csproj
@@ -7,4 +7,7 @@
   <ItemGroup>
     <Compile Include="$(MSBuildProjectName).cs"/>
   </ItemGroup>
+  <ItemGroup>
+    <ProjectReference Include="$(TestSourceDir)Common/CoreCLRTestLibrary/CoreCLRTestLibrary.csproj" />
+  </ItemGroup>
 </Project>
diff --git a/src/tests/managed/Managed.csproj b/src/tests/managed/Managed.csproj
index 305a3dfa0b613b..f622053ed9d452 100644
--- a/src/tests/managed/Managed.csproj
+++ b/src/tests/managed/Managed.csproj
@@ -1,4 +1,9 @@
 <Project Sdk="Microsoft.NET.Sdk">
+  <PropertyGroup>
+      <!-- disable building for mono until https://github.com/dotnet/xharness/pull/1416 is merged -->
+      <DisableProjectBuild Condition="'$(RuntimeFlavor)' == 'mono' and '$(TargetsWindows)' != 'true'">true</DisableProjectBuild>    
+  </PropertyGroup>
+
   <ItemGroup>
     <MergedWrapperProjectReference Include="*/**/*.??proj" />
   </ItemGroup>