diff --git a/src/debug-agent.cc b/src/debug-agent.cc
index 425a08716dc1d5..2e51c89c987075 100644
--- a/src/debug-agent.cc
+++ b/src/debug-agent.cc
@@ -120,11 +120,12 @@ bool Agent::Start(int port, bool wait) {
 
 
 void Agent::Enable() {
-  v8::Debug::SetMessageHandler(MessageHandler);
+  v8::Debug::SetMessageHandler(parent_env()->isolate(), MessageHandler);
 
   // Assign environment to the debugger's context
   // NOTE: The debugger context is created after `SetMessageHandler()` call
-  parent_env()->AssignToContext(v8::Debug::GetDebugContext());
+  auto debug_context = v8::Debug::GetDebugContext(parent_env()->isolate());
+  parent_env()->AssignToContext(debug_context);
 }
 
 
@@ -135,7 +136,7 @@ void Agent::Stop() {
     return;
   }
 
-  v8::Debug::SetMessageHandler(nullptr);
+  v8::Debug::SetMessageHandler(parent_env()->isolate(), nullptr);
 
   // Send empty message to terminate things
   EnqueueMessage(new AgentMessage(nullptr, 0));
diff --git a/src/node.cc b/src/node.cc
index 807cb6a91d1858..2a5fe73333913a 100644
--- a/src/node.cc
+++ b/src/node.cc
@@ -114,6 +114,7 @@ using v8::Integer;
 using v8::Isolate;
 using v8::Local;
 using v8::Locker;
+using v8::MaybeLocal;
 using v8::Message;
 using v8::Number;
 using v8::Object;
@@ -121,6 +122,7 @@ using v8::ObjectTemplate;
 using v8::Promise;
 using v8::PromiseRejectMessage;
 using v8::PropertyCallbackInfo;
+using v8::ScriptOrigin;
 using v8::SealHandleScope;
 using v8::StackFrame;
 using v8::StackTrace;
@@ -1042,7 +1044,8 @@ void SetupDomainUse(const FunctionCallbackInfo<Value>& args) {
 
   // Do a little housekeeping.
   env->process_object()->Delete(
-      FIXED_ONE_BYTE_STRING(args.GetIsolate(), "_setupDomainUse"));
+      env->context(),
+      FIXED_ONE_BYTE_STRING(args.GetIsolate(), "_setupDomainUse")).FromJust();
 
   uint32_t* const fields = env->domain_flag()->fields();
   uint32_t const fields_count = env->domain_flag()->fields_count();
@@ -1065,7 +1068,8 @@ void SetupProcessObject(const FunctionCallbackInfo<Value>& args) {
 
   env->set_push_values_to_array_function(args[0].As<Function>());
   env->process_object()->Delete(
-      FIXED_ONE_BYTE_STRING(env->isolate(), "_setupProcessObject"));
+      env->context(),
+      FIXED_ONE_BYTE_STRING(env->isolate(), "_setupProcessObject")).FromJust();
 }
 
 
@@ -1081,7 +1085,8 @@ void SetupNextTick(const FunctionCallbackInfo<Value>& args) {
 
   // Do a little housekeeping.
   env->process_object()->Delete(
-      FIXED_ONE_BYTE_STRING(args.GetIsolate(), "_setupNextTick"));
+      env->context(),
+      FIXED_ONE_BYTE_STRING(args.GetIsolate(), "_setupNextTick")).FromJust();
 
   // Values use to cross communicate with processNextTick.
   uint32_t* const fields = env->tick_info()->fields();
@@ -1121,7 +1126,8 @@ void SetupPromises(const FunctionCallbackInfo<Value>& args) {
   env->set_promise_reject_function(args[0].As<Function>());
 
   env->process_object()->Delete(
-      FIXED_ONE_BYTE_STRING(args.GetIsolate(), "_setupPromises"));
+      env->context(),
+      FIXED_ONE_BYTE_STRING(args.GetIsolate(), "_setupPromises")).FromJust();
 }
 
 
@@ -1461,8 +1467,8 @@ void AppendExceptionLine(Environment* env,
   // sourceline to 78 characters, and we end up not providing very much
   // useful debugging info to the user if we remove 62 characters.
 
-  int start = message->GetStartColumn();
-  int end = message->GetEndColumn();
+  int start = message->GetStartColumn(env->context()).FromJust();
+  int end = message->GetEndColumn(env->context()).FromJust();
 
   char arrow[1024];
   int max_off = sizeof(arrow) - 2;
@@ -1607,13 +1613,15 @@ static Local<Value> ExecuteString(Environment* env,
   // we will handle exceptions ourself.
   try_catch.SetVerbose(false);
 
-  Local<v8::Script> script = v8::Script::Compile(source, filename);
+  ScriptOrigin origin(filename);
+  MaybeLocal<v8::Script> script =
+      v8::Script::Compile(env->context(), source, &origin);
   if (script.IsEmpty()) {
     ReportException(env, try_catch);
     exit(3);
   }
 
-  Local<Value> result = script->Run();
+  Local<Value> result = script.ToLocalChecked()->Run();
   if (result.IsEmpty()) {
     ReportException(env, try_catch);
     exit(4);
@@ -2371,7 +2379,7 @@ static void Binding(const FunctionCallbackInfo<Value>& args) {
   Local<Object> cache = env->binding_cache_object();
   Local<Object> exports;
 
-  if (cache->Has(module)) {
+  if (cache->Has(env->context(), module).FromJust()) {
     exports = cache->Get(module)->ToObject(env->isolate());
     args.GetReturnValue().Set(exports);
     return;
@@ -2788,15 +2796,20 @@ void StopProfilerIdleNotifier(const FunctionCallbackInfo<Value>& args) {
 
 #define READONLY_PROPERTY(obj, str, var)                                      \
   do {                                                                        \
-    obj->ForceSet(OneByteString(env->isolate(), str), var, v8::ReadOnly);     \
+    obj->DefineOwnProperty(env->context(),                                    \
+                           OneByteString(env->isolate(), str),                \
+                           var,                                               \
+                           v8::ReadOnly).FromJust();                          \
   } while (0)
 
 #define READONLY_DONT_ENUM_PROPERTY(obj, str, var)                            \
   do {                                                                        \
-    obj->ForceSet(OneByteString(env->isolate(), str),                         \
-                  var,                                                        \
-                  static_cast<v8::PropertyAttribute>(v8::ReadOnly |           \
-                                                     v8::DontEnum));          \
+    obj->DefineOwnProperty(env->context(),                                    \
+                           OneByteString(env->isolate(), str),                \
+                           var,                                               \
+                           static_cast<v8::PropertyAttribute>(v8::ReadOnly |  \
+                                                              v8::DontEnum))  \
+        .FromJust();                                                          \
   } while (0)
 
 
@@ -3539,7 +3552,7 @@ static void DispatchDebugMessagesAsyncCallback(uv_async_t* handle) {
   }
 
   Isolate::Scope isolate_scope(isolate);
-  v8::Debug::ProcessDebugMessages();
+  v8::Debug::ProcessDebugMessages(isolate);
   CHECK_EQ(nullptr, node_isolate.exchange(isolate));
 }
 
diff --git a/src/node.h b/src/node.h
index ef1f629d20aa0e..1a67cad420bf70 100644
--- a/src/node.h
+++ b/src/node.h
@@ -221,13 +221,17 @@ NODE_EXTERN void RunAtExit(Environment* env);
 #define NODE_DEFINE_CONSTANT(target, constant)                                \
   do {                                                                        \
     v8::Isolate* isolate = target->GetIsolate();                              \
+    v8::Local<v8::Context> context = isolate->GetCurrentContext();            \
     v8::Local<v8::String> constant_name =                                     \
         v8::String::NewFromUtf8(isolate, #constant);                          \
     v8::Local<v8::Number> constant_value =                                    \
         v8::Number::New(isolate, static_cast<double>(constant));              \
     v8::PropertyAttribute constant_attributes =                               \
         static_cast<v8::PropertyAttribute>(v8::ReadOnly | v8::DontDelete);    \
-    (target)->ForceSet(constant_name, constant_value, constant_attributes);   \
+    (target)->DefineOwnProperty(context,                                      \
+                                constant_name,                                \
+                                constant_value,                               \
+                                constant_attributes).FromJust();              \
   }                                                                           \
   while (0)
 
diff --git a/src/node_contextify.cc b/src/node_contextify.cc
index b3e3d3d051375f..342b46b3517a79 100644
--- a/src/node_contextify.cc
+++ b/src/node_contextify.cc
@@ -140,7 +140,7 @@ class ContextifyContext {
     int length = names->Length();
     for (int i = 0; i < length; i++) {
       Local<String> key = names->Get(i)->ToString(env()->isolate());
-      bool has = sandbox->HasOwnProperty(key);
+      bool has = sandbox->HasOwnProperty(context, key).FromJust();
       if (!has) {
         // Could also do this like so:
         //
@@ -167,9 +167,8 @@ class ContextifyContext {
               "  }\n"
               "})");
 
-          Local<String> fname = FIXED_ONE_BYTE_STRING(env()->isolate(),
-              "binding:script");
-          Local<Script> script = Script::Compile(code, fname);
+          Local<Script> script =
+              Script::Compile(context, code).ToLocalChecked();
           clone_property_method = Local<Function>::Cast(script->Run());
           CHECK(clone_property_method->IsFunction());
         }
@@ -245,12 +244,12 @@ class ContextifyContext {
     Local<String> script_source(args[0]->ToString(args.GetIsolate()));
     if (script_source.IsEmpty())
       return;  // Exception pending.
-    Local<Context> debug_context = Debug::GetDebugContext();
+    Local<Context> debug_context = Debug::GetDebugContext(args.GetIsolate());
     Environment* env = Environment::GetCurrent(args);
     if (debug_context.IsEmpty()) {
       // Force-load the debug context.
       Debug::GetMirror(args.GetIsolate()->GetCurrentContext(), args[0]);
-      debug_context = Debug::GetDebugContext();
+      debug_context = Debug::GetDebugContext(args.GetIsolate());
       CHECK(!debug_context.IsEmpty());
       // Ensure that the debug context has an Environment assigned in case
       // a fatal error is raised.  The fatal exception handler in node.cc
@@ -263,10 +262,10 @@ class ContextifyContext {
     }
 
     Context::Scope context_scope(debug_context);
-    Local<Script> script = Script::Compile(script_source);
+    MaybeLocal<Script> script = Script::Compile(debug_context, script_source);
     if (script.IsEmpty())
       return;  // Exception pending.
-    args.GetReturnValue().Set(script->Run());
+    args.GetReturnValue().Set(script.ToLocalChecked()->Run());
   }
 
 
@@ -526,7 +525,7 @@ class ContextifyScript : public BaseObject {
     else if (produce_cached_data)
       compile_options = ScriptCompiler::kProduceCodeCache;
 
-    Local<UnboundScript> v8_script = ScriptCompiler::CompileUnbound(
+    MaybeLocal<UnboundScript> v8_script = ScriptCompiler::CompileUnboundScript(
         env->isolate(),
         &source,
         compile_options);
@@ -538,7 +537,8 @@ class ContextifyScript : public BaseObject {
       try_catch.ReThrow();
       return;
     }
-    contextify_script->script_.Reset(env->isolate(), v8_script);
+    contextify_script->script_.Reset(env->isolate(),
+                                     v8_script.ToLocalChecked());
 
     if (compile_options == ScriptCompiler::kConsumeCodeCache) {
       args.This()->Set(
@@ -832,7 +832,7 @@ class ContextifyScript : public BaseObject {
     }
 
     if (try_catch.HasCaught() && try_catch.HasTerminated()) {
-      V8::CancelTerminateExecution(env->isolate());
+      env->isolate()->CancelTerminateExecution();
       env->ThrowError("Script execution timed out.");
       try_catch.ReThrow();
       return false;
diff --git a/src/node_internals.h b/src/node_internals.h
index ea83d4d9fc1238..df6d1f4de3fe0e 100644
--- a/src/node_internals.h
+++ b/src/node_internals.h
@@ -22,10 +22,10 @@ struct sockaddr;
         v8::String::NewFromUtf8(isolate, constant);                           \
     v8::PropertyAttribute constant_attributes =                               \
         static_cast<v8::PropertyAttribute>(v8::ReadOnly | v8::DontDelete);    \
-    target->ForceSet(isolate->GetCurrentContext(),                            \
-                     constant_name,                                           \
-                     constant_value,                                          \
-                     constant_attributes);                                    \
+    target->DefineOwnProperty(isolate->GetCurrentContext(),                   \
+                              constant_name,                                  \
+                              constant_value,                                 \
+                              constant_attributes).FromJust();                \
   } while (0)
 
 namespace node {
diff --git a/src/node_os.cc b/src/node_os.cc
index 92f53a9c407fae..f432702792fc0a 100644
--- a/src/node_os.cc
+++ b/src/node_os.cc
@@ -217,7 +217,7 @@ static void GetInterfaceAddresses(const FunctionCallbackInfo<Value>& args) {
     name = OneByteString(env->isolate(), raw_name);
 #endif
 
-    if (ret->Has(name)) {
+    if (ret->Has(env->context(), name).FromJust()) {
       ifarr = Local<Array>::Cast(ret->Get(name));
     } else {
       ifarr = Array::New(env->isolate());
diff --git a/src/node_watchdog.cc b/src/node_watchdog.cc
index 77f93678fb88ff..ac9f304926bac4 100644
--- a/src/node_watchdog.cc
+++ b/src/node_watchdog.cc
@@ -83,7 +83,7 @@ void Watchdog::Async(uv_async_t* async) {
 void Watchdog::Timer(uv_timer_t* timer) {
   Watchdog* w = ContainerOf(&Watchdog::timer_, timer);
   uv_stop(w->loop_);
-  V8::TerminateExecution(w->isolate());
+  w->isolate()->TerminateExecution();
 }
 
 
diff --git a/src/stream_base.cc b/src/stream_base.cc
index 27ae0fee7b1309..648c6d3aa59941 100644
--- a/src/stream_base.cc
+++ b/src/stream_base.cc
@@ -82,8 +82,10 @@ void StreamBase::AfterShutdown(ShutdownWrap* req_wrap, int status) {
     req_wrap_obj
   };
 
-  if (req_wrap->object()->Has(env->oncomplete_string()))
+  if (req_wrap->object()->Has(env->context(),
+                              env->oncomplete_string()).FromJust()) {
     req_wrap->MakeCallback(env->oncomplete_string(), ARRAY_SIZE(argv), argv);
+  }
 
   delete req_wrap;
 }
@@ -371,7 +373,7 @@ void StreamBase::AfterWrite(WriteWrap* req_wrap, int status) {
 
   // Unref handle property
   Local<Object> req_wrap_obj = req_wrap->object();
-  req_wrap_obj->Delete(env->handle_string());
+  req_wrap_obj->Delete(env->context(), env->handle_string()).FromJust();
   wrap->OnAfterWrite(req_wrap);
 
   Local<Value> argv[] = {
@@ -387,8 +389,10 @@ void StreamBase::AfterWrite(WriteWrap* req_wrap, int status) {
     wrap->ClearError();
   }
 
-  if (req_wrap->object()->Has(env->oncomplete_string()))
+  if (req_wrap->object()->Has(env->context(),
+                              env->oncomplete_string()).FromJust()) {
     req_wrap->MakeCallback(env->oncomplete_string(), ARRAY_SIZE(argv), argv);
+  }
 
   req_wrap->Dispose();
 }