diff --git a/.buildkite/run-amd-test.sh b/.buildkite/run-amd-test.sh
index 9274a30e0432..45b20c9447c7 100755
--- a/.buildkite/run-amd-test.sh
+++ b/.buildkite/run-amd-test.sh
@@ -94,6 +94,15 @@ if [[ $commands == *" kernels "* ]]; then
   --ignore=kernels/test_sampler.py"
 fi
 
+#ignore certain Entrypoints tests
+if [[ $commands == *" entrypoints/openai "* ]]; then
+  commands=${commands//" entrypoints/openai "/" entrypoints/openai \
+  --ignore=entrypoints/openai/test_accuracy.py \
+  --ignore=entrypoints/openai/test_audio.py \
+  --ignore=entrypoints/openai/test_encoder_decoder.py \
+  --ignore=entrypoints/openai/test_oot_registration.py "}
+fi
+
 PARALLEL_JOB_COUNT=8
 # check if the command contains shard flag, we will run all shards in parallel because the host have 8 GPUs. 
 if [[ $commands == *"--shard-id="* ]]; then
diff --git a/.buildkite/test-pipeline.yaml b/.buildkite/test-pipeline.yaml
index 37207b677a1e..379a67c4c8cf 100644
--- a/.buildkite/test-pipeline.yaml
+++ b/.buildkite/test-pipeline.yaml
@@ -84,7 +84,7 @@ steps:
 - label: Entrypoints Test # 20min
   working_dir: "/vllm-workspace/tests"
   fast_check: true
-  #mirror_hardwares: [amd]
+  mirror_hardwares: [amd]
   source_file_dependencies:
   - vllm/
   commands: