Deep learning framework for TCR-peptide binding prediction using evolutionary protein representations, physicochemical cross-attention, and hierarchical contrastive learning. Integrates ESM encoders with Atchley factor biases for superior generalization to novel peptides.
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Deep learning framework for TCR-peptide binding prediction using evolutionary protein representations, physicochemical cross-attention, and hierarchical contrastive learning. Integrates ESM encoders with Atchley factor biases for superior generalization to novel peptides.
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Ong-Research/TCR-ECHO
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Deep learning framework for TCR-peptide binding prediction using evolutionary protein representations, physicochemical cross-attention, and hierarchical contrastive learning. Integrates ESM encoders with Atchley factor biases for superior generalization to novel peptides.
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