Modification to the annotate_sex pipeline to allow sex ploidy estimation using only variants instead of ref blocks
#445
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klaricch
requested changes
Apr 1, 2022
klaricch
requested changes
Apr 1, 2022
klaricch
approved these changes
Apr 1, 2022
…b.com/broadinstitute/gnomad_methods into jg/sex_ploidy_variants
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During testing of our gnomAD v4 exome dataset we determined that there was better separation of x-ploidy values by using only the variant dataset to determine the mean DP of chromosome X rather than the reference blocks.
This PR is dependent on PR change to the VDS
impute_sex_chromosome_ploidymethod: hail-is/hail#11701