On windows 11 x64 with latest main, after nuking artifacts:
.\build.cmd -rc Checked -lc Release /bl
Z:\runtime\src\coreclr\jit\codegenxarch.cpp:715
Assertion failed 'operand->isUsedFromReg()' in 'System.Uri:InternalIsWellFormedOriginalString():bool:this' during 'Generate code' (IL size 831; hash 0x83c53887; FullOpts)
Z:\runtime\artifacts\bin\Crossgen2Tasks\Debug\net10.0\Microsoft.NET.CrossGen.targets(464,5): error MSB6006: "Z:\runtime\artifacts\bin\coreclr\windows.x64.Checked\x64\crossgen2\crossgen2.exe" exited with code -2147483645. [Z:\runtime\src\installer\pkg\sfx\Microsoft.NETCore.App\Microsoft.NETCore.App.Runtime.CoreCLR.sfxproj]
Still looking into this further but wanted to file it in case someone else is hitting it.